| 1 | In New York in 1890, William Kemmler became the first person to be executed by what method? Electric chair |
| 2 | In 1960, which country became the first in the world to have a female Prime Minister? Sri Lanka |
| 3 | In 1520, who became the first explorer to sail across the Pacific Ocean? Ferdinand Magellan |
| 4 | What was the name of the first dog to orbit the earth? Laika |
| 5 | French woman Isabelle Dinoire was the first person to receive a transplant of which body part in 2005? Face (after being mauled by her dog) |
| 6 | Who led the first expedition to reach the North Pole by automobile? Jeremy Clarkson (in a modified Toyota Hilux for Top Gear in 2007) |
| 7 | What was the world's first jet-driven airliner to enter commercial service? The Comet |
| 8 | Situated on the north coast of Scotland, the UK's first fast-breeder nuclear reactor is situated where? Dounreay |
| 9 | In 1983, Colin Pirchfork became the first criminal to be convicted for murder by the use of what evidence? DNA fingerprinting |
| 10 | Born in 1978, what is the name of the UK's first “test tube baby”? Louise Brown |